THC-Free Full-Spectrum CBD: Transforming THC to CBN | Curatio
Chances are, you're reading this because you've heard about the use of cannabis and hemp for medical reasons. They contain cannabinoids similar to compounds our own bodies produce to regulate many important functions. The most abundant cannabinoid in hemp is cannabidiol (CBD) which is non-psychoactive, Tetrahydrocannabinol (THC) is at low trace levels. Although THC has powerful medicinal properties, its psychoactive effects make it less desirable for therapeutic purposes. What if there was a way of preserving its health benefits while making it safer to use and not intoxicating?
Full-spectrum CBD, Broad Spectrum CBD and Isolates
The term "full-spectrum CBD" refers to a preparation like Curatio, which includes all of the cannabinoids, terpenes, flavonoids, triglycerides, esters, phenols and proteins in its hemp. Researchers have found that full-spectrum CBD products are more effective than broad spectrum products and CBD isolates.
The term “broad spectrum” is misleading because the process of removing THC also removes most of the other cannabinoids. The final product has a secondary cannabinoid content that does not exceed 2 percent. Curatio's secondary content exceeds 15 percent. CBD isolate only consists of the CBD molecule and is the least effective when compared to full spectrum.
Cannabinoids, terpenes and triglycerides work better in combination with each other. This greater and longer-lasting CBD activity is known as the “entourage effect,” discovered in 1998. Broad spectrum products and isolates do not produce the entourage effect. Scientists have proposed four mechanisms for this effect: multiple, rather than single targets; improved solubility and bioavailability of the agents; agent interactions reducing bacterial resistance; and modulation of adverse events.
Making THC-free CBD using CBN
For its THC-free CBD, Curatio uses an non-GMO hemp, grown in Colorado. Curatios hemp provides full-spectrum results without the psychoactive effects of THC. Curatio's proprietary CBD profile features a unique ratio of cannabinoids, flavonoids, terpenes and triglycerides, as mentioned above. These components work synergistically, resulting in the entourage effect.
Among the cannabinoids is cannabinol (CBN), which alleviate pains and inflammation. It has weak psychoactive but non-intoxicating effects. When THC is exposed to heat and light, it slowly turns into CBN. Curatio uses a patented oxidation process to convert the 3 percent THC content in its hemp to the CBN cannabinoid, in a 1:1 conversion.
Like THC, CBN plays an important role in producing the entourage effect and like THC, binds to the CB1 receptor but without psychoactive effects. Research suggests it has therapeutic potential for conditions including insomnia, pain, anxiety and depression. With CBN, Curatio has demonstrated that the traditional view that THC must be part of full-spectrum CBD is not accurate.
As a full-spectrum CBD formula with 3 percent CBN, Curatio is more powerful than other products which contain only 0.3 percent THC — the legal limit.
CBD tinctures are oil-based. Their absorption rates in the body are nearly the same, usually ranging from 6 to 8%. Since CBD oil is hydrophobic (it repels and does not combine with water), it is not well absorbed in the gut. Curatio uses sonification (sound waves) to generate enough shear break into millions of microscopic drops, only 4 nanometers wide, that can disperse in water-based preparations. This nanoemulsion technique allows absorption even before the product reaches the stomach and increases its uptake by 10x , resulting in a final absorption rate of at least 70%. Because of more rapid onset and duration of action, smaller doses can achieve the same benefits.
Broad spectrum CBD oil is also THC-free. The term is misleading because the process of removing the THC also removes most of the other cannabinoids. The final product has a secondary cannabinoid content that does not exceed 2 percent. Curatio's content exceeds 15 percent.
To produce full-spectrum CBD water-soluble spray and drops , Curatio uses hemp and converts its THC to CBN, thereby reducing psychoactivity and boosting the entourage effect. Nanoemulsion technology increases bioavailability and potency of the final product. Finally, it is tested by an independent lab three times. First, the raw ingredient is assayed, then the nanoemulsion, and lastly, the final product.
Lexa W. Lee is a former family physician, research fellow in immunology, lecturer and medical journalist. She also writes about consumer health issues.
- https://curatiocbd.com/collections/all/products/mct-tincture-500 https://www.hielscher.com/ultrasonic-cannabis-oil-emulsion.htm